Article: Activation of alpha1-adrenoceptors increases firing frequency through protein kinase C in pyramidal neurons of rat visual cortex.
Full Text (publisher's website) ;
Article Metadata ;
Article Data (extracted)
Kobayashi M; Sasabe T; Shiohama Y; Koshikawa N
Neurosci. Lett., 2008
Table 2The effects of phenylephrine, isoproterenol, phorbol ester and chelerythrine on repetitive firing properties
| Slope | x-intercept |
| Early phasea (spikes/nA) | Late phase (spikes/nA)b | Early phase (nA)a |
Control | 40.7±4.9 | 12.1±6.3 | 0.2±0.1 |
Phenylephrine | 53.6±4.5* | 29.1±5.4** | 0.1±0.1* |
n | 16 | 14 | 16 |
Control | 29.1±4.4 | 9.1±4.5 | 0.3±0.1 |
Isoproterenol | 45.6±3.8** | 33.0±4.3*** | 0.1±0.1* |
n | 14 | 14 | 14 |
|
Control | 41.1±7.5 | 20.6±8.9 | 0.2±0.1 |
Phorbol ester | 61.1±6.1* | 26.3±8.6 | 0.0±0.0** |
n | 8 | 8 | 8 |
|
Chelerythrine | 51.3±6.4 | 31.8±11.5 | 0.2±0.1 |
+Phenylephrine | 55.1±9.3 | 32.1±8.9 | 0.0±0.0 |
n | 7 | 4 | 7 |
aEarly phase: 0ms≤t≤300ms.bLate phase: 300ms<t≤600ms.*P<0.05 (paired t-test).**P<0.01 (paired t-test).***P<0.001 (paired t-test).
Inferred neuron-electrophysiology data values
Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |